Autologous Stem Cells · Fundamental Regeneration

Bone Marrow Stimulation Stem Cell Therapy
Regenerate Your Rotator Cuff with Your Own Cells

Rather than suppressing pain, this therapy uses your own bone marrow's stem cells to fundamentally regenerate damaged rotator cuff tissue. Effective even when other injection therapies have repeatedly failed.

Autologous
Cell Source
None
Foreign Body Reaction
30–60 min
Duration
Same day
Discharge
How It Works

The Science Behind Bone Marrow Stem Cell Therapy

1

Mobilizing mesenchymal stem cells (MSCs)

Bone marrow contains mesenchymal stem cells (MSCs) with the ability to differentiate into tendon and cartilage tissue. Bone stimulation mobilizes these cells toward the injury site, initiating a natural regenerative response.

2

Targeting the critical zone

The rotator cuff has a "critical zone" near the bone attachment with poor blood supply — the most common site of tears. Bone marrow stimulation delivers regenerative factors directly to this area, overcoming the vascular limitation.

3

Applicable even after injection therapy failures

Patients who have failed steroid injections, PDRN, or prolotherapy are still candidates. Bone marrow stimulation works via a completely different regenerative mechanism, making it effective even when previous treatments have not worked.

Indications

Who Is a Good Candidate?

Partial rotator cuff tear (mild to moderate)
Repeated failure of injection therapy (steroid, PDRN)
Avoidance of surgery for partial tears
Elderly patients with high surgical risk
Partial tear with significant tendon degeneration
When combined with ligament regeneration injection

Not ideal for full-thickness tears with muscle atrophy

Complete full-thickness tears with significant muscle atrophy or fatty degeneration may require surgical repair. Candidacy is evaluated by Dr. Lee after imaging review.

Clinical Evidence

Evidence-Based Regenerative Medicine

Scientific Basis

Bone marrow-derived mesenchymal stem cells (MSCs) have been shown to differentiate into tenocytes and chondrocytes under appropriate stimulation. The critical zone of the rotator cuff — approximately 1 cm from the greater tuberosity insertion — has historically poor vascularity and limited healing capacity. Bone marrow stimulation techniques have demonstrated ability to improve cell recruitment to this hypovascular zone, improving tendon healing outcomes in multiple published studies.

Recovery Timeline

What to Expect After Treatment

Week 1

Mild soreness at the procedure site. Ice and rest recommended. Light daily activities are generally possible.

Month 1

Early regenerative response begins. Gradual reduction in pain and improvement in range of motion. Follow-up ultrasound assessment.

Month 3

Significant tissue regeneration in progress. Rehabilitation exercises initiated. Return to moderate activity.

Month 6

Tendon healing confirmed by ultrasound. Most patients experience substantial functional improvement. Full activity gradually resumed.

Regenerate Your Rotator Cuff with Your Own Stem Cells

Dr. Lee evaluates your condition and determines the optimal regenerative approach

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